Rolle was the eldest son of John Rolle (1679–1730), Member of Parliament for Devon (who had declined the offer of an earldom by Queen Anne) by his wife Isabella Walter, daughter of Sir William Walter, 2nd Baronet, of Saresden, Oxfordshire.

[1] Rolle succeeded his father as Member of Parliament for Devon on the latter's death in 1730, and held the seat until 1741.

Lord Rolle died unmarried in August 1750, aged 41, when the barony became extinct.

for £1,127.3s.4d., of the Manors of Litlam alias Littelham and Exmouthe belonging to the late Monastery of Shirbourne, Dorset, in as full manner as the last Abbot held the same; also the messuage formerly in the tenure of Katherine Lytton in the parish of St. Peter-the-Less, in the ward of Beynardes Castell in London; which messuage lately belonged to the late Monastery of Croxden, Staffs and is worth 26s.8d.

Also the hundred of Budlegh alias East Budleigh which came to the King's hands by the attainder of Henry Courteney, late Marquis of Exeter.