Henry William Seymour (July 21, 1834 – April 7, 1906) was a politician from the U.S. state of Michigan.

Seymour engaged in mercantile pursuits in Brockport until 1872 when he moved to Sault Ste.

In a special election on February 14, 1888, to fill the vacancy caused by the death of Seth C. Moffatt, Seymour was elected as a Republican from Michigan's 11th congressional district to the 50th Congress, serving from February 14, 1888, to March 3, 1889.

He was an unsuccessful candidate for re-nomination in 1888, losing to fellow Republican Samuel M. Stephenson in the primaries.

Henry W. Seymour died at the age of seventy-one, while on a visit, in Washington, D.C.