The arena can be used to host gymnastics, handball, volleyball, basketball, boxing, wrestling, fencing, badminton, table tennis, Judo, MMA, and weightlifting, with its primary use being to host basketball games.

On 7 November 2013, Panathinaikos hosted a EuroLeague game against Lokomotiv Kuban at the arena, drawing an attendance of 5,192 people.

[3] On 15 October 2015, Olympiacos hosted a EuroLeague game against Cedevita Zagreb at the arena, drawing an attendance of 5,006 people.

The arena also hosted most of the senior men's Greek national basketball team's home games during the qualification round for the 2019 FIBA World Cup.

In October 2018 it was announced that the arena will host the 2019 Greek Cup Final for a second consecutive year after the 2018 one.