Written by Damian Kulash Jr., the three-minute "Here It Goes Again" is set in common time at a "Moderately fast rock" tempo of 144 beats per minute.

[2] Kulash also sang and played the guitar in the original mix, which was produced by Tore Johansson with co-production done by Eric Drew Feldman, Howard Willing and Ken Sluiter.

[3] On the American Billboard Hot 100 chart, issue dated September 16, 2006, "Here It Goes Again" debuted at number 87,[4] and by the next week it rose to its peak into the top 40 at 38.

[12] The music video of this song is a performance of the band dancing on eight treadmills, arranged in two rows of four and in alternating opposite directions, in a single continuous take.

Choreographed and co-directed by the band and lead singer Damian Kulash's sister Trish Sie, it took 17 attempts to complete the video.

9 on "The Must List" in the August 18, 2006, issue of Entertainment Weekly: "The votes have been tallied, and this year's award for Best Use of Treadmills in an Alt-Pop Music Video goes to ...

[30] This song featured in the NBC sitcom Scrubs in the sixth-season episode "My Mirror Image,"[31] as well as in the 2011 film Bucky Larson: Born to Be a Star.