Following the end of World War II Queen Wilhelmina Witte was appointed as acting Mayor of Bergen op Zoom, taking office on 1 May 1945.

After the election of 1952 Witte was appointed as Minister of Reconstruction and Housing in the Cabinet Drees II, taking office on 2 September 1952.

After the election of 1956 Witte continued in the post as the newly renamed Minister of Housing and Construction in the Cabinet Drees III, taking office on 13 October 1956.

Witte served as acting Minister of Transport and Water Management from 10 October 1958 until 1 November 1958 following the resignation of Jacob Algera.

On 14 October 1966 the Cabinet Cals fell and continued to serve in a demissionary capacity until it was replaced by the caretaker Cabinet Zijlstra with Witte taking a leave of absence as Mayor and was again appointed as Minister of Housing and Spatial Planning, taking office on 22 November 1966.