Hermann Friedrich Otto (born 30 July 1751 in Lockenhaus (Léka), Vas County, Kingdom of Hungary; died 2 November 1810 in Hechingen) was the ruling Prince of Hohenzollern-Hechingen from 1798 until 1810.

From his mother, Countess Anna Maria of Hoensbroech-Geulle ( 8 May 1729 – 26 September 1798), Prince Hermann inherited his Dutch holdings.

After the transfer of the left bank of the Rhein to France as part of war reparations, he tried to find money for the beautification of Hechingen and the improvement of roads.

Prince Hermann was not generally a man of compromise, he was a bizarre personality, his nature was suspicious and that of a micro-manager; he concerned himself with the external details of administration.

The Confederation of the Rhine Acts rescued the independent existence of the Hechinger Princes, however he was in no way given an extension of power, neither based on landowner nor on rights of sovereignty.

Deeply afflicted by the humiliation of Prussia and Austria, Prince Hermann Friedrich Otto died on 2 November 1810.

The couple had one son: His third wife became Countess Maria Antonia Monika of Waldburg-Zeil zu Wurzach on 26 July 1779 (* 6 June 1753; † 25 October 1814), widow of Count Joseph Anton Damian Albert of Oettingen-Baldern-Katzenstein (1720-1778), daughter of Count Franz Ernst Joseph Anton of Waldburg-Zeil-Wurzach (1704-1781) and his wife, Countess Maria Eleonore of Königsegg-Rothenfels (1711-1766).