The hospital is located at San Lázaro and Belascoaín streets in Centro Habana.

At the time of the Revolution in 1959, the building was only partially completed - it was to be the Banco Nacional de Cuba and some of its dependencies such as the Stock Exchange.

The decision was eventually made to complete the construction and turn it into a hospital, which was finally opened in 1982, 23 years later.

The hospital was named after the Ameijeiras Brothers, which the Cuban state considers to be heroes of the Revolution.

[4] In 1999 the Miami Herald reported that a government crackdown on corruption had extended to Hermanos Ameijeiras, uncovering that three top officials there had mishandled hard-currency income and as a result were fired or forced to resign.