[8] In the 1990s, operators of the facility determined that it was inadequate to meet the modern needs of its residents and sought to build a new structure elsewhere.

[9] On 20 June 2009, the museum was opened by Dutch Queen Beatrix and Russian President Dmitry Medvedev.

[10][11] During the more than 300 years that residents were housed in the Amstelhof, several renovations took place on the building interior and wings were added to provide needed space.

While some areas were restored to their original appearance, many existing walls were removed and spaces reconfigured to accommodate the museum's needs.

On 3 March 2022, the museum severed ties with the State Hermitage in St. Petersburg because of the Russian invasion of Ukraine, which began a week prior.