Established in 1965 in Herzeliya, Israel, the museum's main focus is Israeli and international contemporary art.

The museum building was designed by Israel Prize laureate architect Yaakov Rechter.

It holds different activities in the fields of video art and photography, including workshops and courses.

[3] The Herzliya Museum of Contemporary Art is known for promotion of collaboration between Israeli and Palestinian artists by showing group exhibitions and organizing meetings and workshops for artists to work together.

[6] The museum began with a small collection of paintings, most of which were donated by Herzliya residents, led by co-founder Eugene da Villa,[7] in the early 1960s, that were exhibited in its initial location, an apartment at 15 Bar Ilan Street.