Higashi-Ōdate Station (東大館駅, Higashi-Ōdate-eki) is a railway station located in the city of Ōdate, Akita Prefecture, Japan, operated by the East Japan Railway Company (JR East).

Higashi-Ōdate Station is served by the Hanawa Line, and is located 103.3 km from the terminus of the line at Kōma.

Higashi-Ōdate Station was opened on July 1, 1914 on the privately owned Akita Railways, serving the town of Ōdate, Akita.

The line was nationalized on June 1, 1934, becoming part of the Japanese Government Railways (JGR) system, which became the Japan National Railways (JNR) after World War II.

The station was absorbed into the JR East network upon the privatization of the JNR on April 1, 1987.