[1] When the Tōkaidō Shinkansen and Shin-Osaka Station opened in 1964, the original plan was to close Higashi-Yodogawa (only 0.7 km (0.43 mi) from Shin-Osaka in what was then a largely rural area), but neighborhood residents' objections succeeded in keeping the station open.

[2][3] The original station was demolished and replaced by a new building in 2019.

Along with the new facility, several roadway grade crossings were closed in the process to facilitate better traffic flow on surrounding roads that were often backed up due to long closures for rail traffic.

The station has two island platforms, each of which exclusively serves up or down trains.

This Osaka Prefecture railroad station-related article is a stub.