High Bridge is an unincorporated community and census-designated place in Jessamine County, Kentucky, United States.

Standing 275 feet (84 m) over the river between the Palisades, it first carried both passenger and freight trains.

Freight trains of the Norfolk Southern Railway still use this bridge several times a day.

The Palisades were a popular spot for picnics and dances, as breezes from the river gorge kept it comfortable.

A brand of bottled water named for the community depicts the bridge on its label.

Bethel Academy, the first Methodist school west of the Appalachians, was established in the High Bridge vicinity in 1790.

Kentucky Route 29 leads northeast from High Bridge 4.5 miles (7.2 km) to Wilmore, and Nicholasville, the Jessamine county seat, is 10 miles (16 km) northeast of High Bridge.