The high commissioner for Palestine was the highest ranking authority representing the United Kingdom in the mandated territories of Palestine, and the high commissioner for Transjordan was the highest ranking authority representing the United Kingdom in Transjordan.

These posts were always held simultaneously by a single individual after the high commissioner for Transjordan was established in 1928.

The British representative to Amman was "responsible to the high commissioner in his role as representative of the mandatory power, but not in his capacity as head of the Palestine administration.

The office commenced on 1 July 1920, before the commencement of the Mandate on 29 September 1923, and replaced the British military occupation under the Occupied Enemy Territory Administration, which had operated in Palestine in 1917–1918.

When the office of high commissioner was vacant, or the high commissioner was unable to perform his duties for some reason, a person who was usually the chief secretary of the government of Palestine was appointed to perform the same duties with the same powers.