In 1472, Crumpsall was held in socage by James Radcliffe subject to an annual rent of ten shillings.

One part was sold to Thomas Egerton, 1st Earl of Wilton and another, 188 acres, to William Marsden of Liverpool.

Oldham's Tenement, 45 acres, was sold to the Guardians of the Poor of Manchester in 1855 as a site for the new workhouse, later known as Springfield Hospital.

Pendleton Tenement was bought by the Delaunay family and later sold to the Prestwich Poor law union as the site for a workhouse.

[3] Crumpsall was rural in character during the early part of the 19th century, however, the necessity to house Manchester's growing population of mill workers saw the area become more urbanised.

In January 2003 Detective Constable Stephen Oake, a Greater Manchester Police officer, was fatally stabbed whilst arresting a suspected terrorist in a house on Crumpsall Lane.

Lower Crumpsall is situated in the Irk Valley, which forms its northern boundary with the neighbouring suburb of Blackley at Tetlow Bridge.

[24] Howard Jacobson was brought up in Crumpsall and some of his novels, Kalooki Nights and The Mighty Walzer feature descriptions of Jewish life in the area.

[25] Actor and singer Don Estelle (Gunner "Lofty" Sugden in It Ain't Half Hot Mum), real name Ronald Edwards, was born and raised in Crumpsall.

Jason Orange of the boy band Take That was born at North Manchester General Hospital in Crumpsall.

[27] English grime artist Aaron Davis, stage name Bugzy Malone was born in Crumpsall.