The highway ran from Neenah to Brillion before about 1986, when the section from Hilbert to Brillion was turned back to Calumet County, which now maintains it as County Trunk Highway PP (CTH-PP).

As it reaches downtown, WIS 114 transitions north onto Commercial Street.

As it enters Menasha, WIS 114 transitions onto Washington Avenue and then onto Tayco Street.

It then turns east along Third Street, intersects WIS 47, and then northeast along Plank Road.

After the road bends east, WIS 114 then begins to run concurrently with US 10.