Highway 60 or (Hebrew: כביש שישים, Kvish Shishim; Arabic: الطريق السريع ستين at-Tariq as-Sarie Sitiin) is a south–north intercity road in Israel and the Palestinian West Bank that stretches from Beersheba to Nazareth.

[2] Due to it running through a mainly rural setting, many of the junctions along its route feature hitchhiking posts called trempiadas.

The sections north and south of the West Bank and through Jerusalem are closed to green (Palestinian Authority) license plates.

[citation needed] In 2024, the project to build a second bridge and tunnel parallel to the first, thus expanding the road to two lanes in each direction, was completed.

At its junction with David Remez Street, in the Abu Tor neighborhood, Route 60 narrows and descends into the Hinnom Valley, curving around Sultan's Pool directly under Mount Zion.

The freeway then bypasses Shuafat with one of the longest and highest bridges in the country, feeding into Beit Hanina and Pisgat Ze'ev with two more interchanges.

Route 60 was a central scene of violence during the al-Aqsa Intifada, which was in part defined by the thousands of shooting attacks on its Israeli traffic, including hundreds of casualties.