[2] The game begins in New Mexico where Amber, en route to California, comes across Marina, who just had her car run out of gas in the middle of the desert.

[3] Marina had been in search of a recently-hidden treasure that attracted many other travelers; Amber had been unaware of this situation until the two are told about it at a gas station.

Kaplan also noted that the game "ended up being unexpectedly successful," stating that "it found an audience of primarily LGBT readers who appreciated what they felt was a more realistic approach to same-sex relationships.

[1] Mitch Jay Lineham of PCGamesN called Highway Blossoms "one of the finest yuri – and romance – visual novels on Steam", praising its "heartwarming story" and "stunning, atmospheric soundtrack.

"[13] Jade King of TheGamer wrote that "Highway Blossoms is so soft and sweet, its narrative outfitted with minimal stakes as it hopes to take us on a journey that is equally warm and mysterious."

"[3] Erica Friedman of Okazu rated the game 8/10 points and generally praised it, saying that the writing of Amber and Marina kept her interested in the story and that she appreciated the game for its differences from other yuri visual novels, particularly the choice to set the story on a road trip rather than the more common setting of a high school.