His Toughest Case (German: Sein großer Fall) is a 1926 German silent crime film directed and co-written by Fritz Wendhausen and starring Alexander Murski, Christa Tordy and Olga Chekhova.

[1] It was shot at the Babelsberg Studios in Berlin.

[2] The film's art direction was by Hans Jacoby.

It premiered at the Ufa-Palast am Zoo.

This article related to a German silent film is a stub.