"Hit Me with Your Best Shot" is a song recorded by American rock singer Pat Benatar and written by Eddie Schwartz.

It was particularly popular on album-rock radio stations, peaking at number 1 on the US Tunecaster Rock Tracks chart.

"Hit Me with Your Best Shot" sold well over a million copies in the U.S., achieving a gold certification by the RIAA.

In a 2022 interview, Benatar told USA Today that she would no longer perform the song in protest of mass shootings in the United States.

Artists who have performed the song live include singer-songwriter Kelly Clarkson, whose version of "Hit Me with Your Best Shot" received praise by Time.