Hitman's Wife's Bodyguard is a 2021 American action comedy film directed by Patrick Hughes and written by Tom O'Connor and Brandon and Phillip Murphy.

In the film, suspended bodyguard Michael Bryce (Reynolds) must once again team up with hitman Darius Kincaid (Jackson) and his wife, Sonia (Hayek), to stop a madman (Banderas) from launching a terror attack on Europe.

Michael Bryce, haunted by the loss of his client Takashi Kurosawa by Darius Kincaid, is temporarily retired from being a bodyguard and is on a sabbatical vacation while waiting for reinstatement of his license.

Bryce and the Kincaids are caught by O'Neil, who reveals the mobster Carlo they killed was his informant and was about to buy a hard drive that would give him coordinates to a cyberattack by Aristotle.

The trio manages to infiltrate the party and make the purchase while being informed that they are to meet the buyer at Florence, but Sonia is handcuffed with an explosive device if she loses the coordinates in a case.

Bryce is recognized by a former client, compromising their position, resulting in a shootout; however, they manage to escape before Interpol agents storm in.

Bryce and Darius compose themselves before Sonia calls them, who reveals that she is manipulating Aristotle and he's sending a hitman squad to kill them.

[8] In March 2019, Frank Grillo, Morgan Freeman, Antonio Banderas and Tom Hopper joined the cast of the film, with Richard E. Grant reprising his role from the first.

[7][13] Filming took place in Italy (Trieste), Croatia (Rovinj, Rijeka, Karlovac, Zagreb, Jastrebarsko, Pisarovina, Motovun, Buje, Vodnjan, Lim Channel and Biševo),[14][15] Slovenia, Bulgaria and United Kingdom.

The site's critics consensus reads: "Despite the charms of its ensemble, The Hitman's Wife's Bodyguard fails to protect the audience from repetitive and tired genre tropes.

[2] Alonso Duralde of the TheWrap wrote: "Hitman's Wife Bodyguard is a comedy with not one legitimate laugh and an action movie where cars keep blowing up while the A-listers yell at each other, as though that were inherently amusing or entertaining.

"[25] In June 2021, Patrick Hughes stated that a third film is in development with the basic plot including an additional main cast member, already mapped out.