The park was established by the businessman Anton Kröller and his wife Helene Kröller-Müller as a private estate in 1909.

Due to worsening economic conditions the building of the museum was halted and the couple found themselves unable to keep the estate.

In 2007 a solution was reached by charging reduced fees for cyclists who spend only a limited amount of time within the confines of the park.

The Kröller-Müller Museum houses the art collection of the Kröller-Müller couple and includes numerous important works by artists such as Vincent van Gogh, Pablo Picasso, Odilon Redon, Georges-Pierre Seurat, Auguste Rodin and Piet Mondrian among others.

As mouflon is critical to the conservation of specific biotopes on which other ground species are dependent, action against the wolves may be considered.