Kyle Broflovski and Stan Marsh confront him with photos documenting how Randy himself has dressed as Columbus many times throughout his life, from his wedding to as recently as 2013.
When Randy is informed by the DNA and Me staff of an "irregularity" from his test, they take a second, anal swab from him, in order to obtain more accurate results.
He is informed that his DNA most closely matches Caucasian British person, and that 2.8% of it is Neanderthal, which cross-bred with modern homo sapiens.
This episode focused a bit less on topical humor and headlines, opting instead for a hilarious, Randy-driven storyline that hearkened back to the show's golden era.
"[3] Writing for Den of Geek, Chris Longo gave it 3 out of 5 stars, and stated "What's been the saving grace for this show in the last decade has been using Randy Marsh as the wrench thrown into their playtime and the boys having to make the decision whether or not to dig him out of whatever mess he's created.
For the third week in a row we get a fairly topical episode, as Randy is hell bent on removing the honors bestowed on Christopher Columbus.