Established by an 1824 law and organized in the following year,[2]: 16  Holmes County has possessed three courthouses, all of which have been located at the same site in Millersburg.

Yost, this three-story courthouse comprises such elements as rough stone walls with smooth trim, a colonnaded porch with Ionic columns surrounding the main entrance, and a prominent pediment on the northern side.

[4] From its completion until the 1950s, the courthouse featured a statue of Lady Justice located atop the northern pediment, but its deterioration led local officials to place it in storage for many years until area lawyers paid for its restoration.

Lesser elements of the building's architecture include steel details, ornamental columns and pilasters closer to the mansard roof, plastered ceilings, a state of Lady Justice in the center of the tiled floor in the building's lobby, and towers on the courthouse's corners.

Because of the county's exceptionally large Amish population, the courthouse features a parking area with use restricted to horses and buggies.