It is a freeware fan game featuring VTubers from Hololive Production with gameplay inspired by Vampire Survivors and Magic Survival.

Each time the player levels up they can select 1 of 4 random weapons, items, or skills to upgrade their character.

Characters the player has unlocked in the main game will also visit their house, and sometimes assist them with fishing and farming.

This exceeded the developer's expectations, forcing them to temporarily disable the game's online leaderboards due to the server being overloaded.

[7] In 2023 Yu received permission from Hololive's parent company Cover Corporation to release HoloCure on Steam as a non-commercial fan game.

Yu stated that he wasn't interested in monetizing Holocure and that he earned enough working as an animator to fund the game's low development costs.

"[14] Wood also noted the game received "glowing" reviews from audiences, gaining 99% positive user ratings, and 45,000 concurrent players when it released on Steam.

[15] Ed Thorn from Rock Paper Shotgun discussed HoloCure saying "I am taken aback by how good it is," and compared it to Vampire Survivors noting that "HoloCure is a much slower burn when it comes to fulfilling the power fantasy, and the interplay of its many menus and investment pots might be a bit much for some.

[16] Cover staff cited HoloCure and Idol Showdown as their direct inspiration for the establishment of the Holo Indie brand.