Holon–Wolfson railway station is a railway station on the border of Holon and Jaffa in the south of Tel Aviv-Yafo Municipality, on the Rosh HaAyin–Beersheba line.

On rush hours there is a train every 15 minutes each direction.

Some of the southbound trains terminate at Rishon LeZion Moshe Dayan or Ashkelon and do not continue to Be'er Sheva.

Nearby the station and Wolfson Medical Center, there is a bus terminal with local bus routes that link the station to Holon, Bat Yam, Rishon LeZion and southern Tel Aviv.

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