St. Mary's Academy was coeducational for grades 1–6; however, the high school was only for young ladies.

St. George's College began in the basement of Amarillo's Sacred Heart Cathedral.

Mounting maintenance problems forced Alamo to move to the west wing of St. Joseph Catholic School in 1990.

It was renamed Holy Cross Catholic Academy in 2000 after a complete renovation of the school.

[3] Holy Cross Catholic Academy Debate team regularly competes in the following events: Lincoln-Douglas Debate, Public Forum Debate, Extemporaneous Speaking, Impromptu Speaking, Original Oratory, Prose and Poetry Interpretation, and Interpretation events.