Church of the Holy Cross (Armenian: Սուրբ Խաչ, Sourp khach; Arabic: كنيسة الصليب المقدس) is an Armenian Catholic Church in the Ouroubeh district of Aleppo, Syria.

During the Syrian Civil War and after the break-up of the Battle of Aleppo in 2012, the seat of the Armenian Catholic Archeparchy of Aleppo was temporarily moved to the Holy Cross Church, as the original seat of the diocese the Cathedral of Our Mother of Reliefs was frequently being shelled by the Islamist rebels.

As of April 2010, Father Nerses Zabbarian is the parish priest of Holy Cross church.

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