It was built from 1902 to 1903 by the priest and architect Alexander Scoles in the Gothic Revival style.

It was named after the old ruined medieval Chapel of the Holy Ghost in the town.

It is located on the corner of Chapel Hill and Sherborne Road, north of Basingstoke railway station near the town centre.

[3] From the early 1800s, priests came from Woolhampton to celebrate Mass in Basingstoke for the local Catholic population.

In 1877, Holy Ghost Chapel and a schoolroom were opened on the site.