Anson built St James' Church in Danes Road, Rusholme, but Worsley arranged for Holy Trinity to be consecrated before its building was complete.

[3] The church cost £4,000 (equivalent to £490,000 in 2023)[4] (excluding the stained glass), and when built it could accommodate between 650 and 700 people.

[3][6] The church was consecrated on 26 June 1846 by Rt Revd John Bird Sumner, Bishop of Chester, although the spire was not completed until 1850.

Its middle stage contains three-light windows with crocketted gables, above which are paired bell openings.

The stained glass in the chancel forms a memorial to the Worsley family and dates from 1849 to 1850.

In the north aisle is a window dated 1871 with glass made by Lavers, Barraud and Westlake.