Homer and Eddie is a 1989 American comedy film starring Whoopi Goldberg and Jim Belushi and directed by Andrei Konchalovsky.

The film received generally poor reviews from critics.

A homicidal escaped mental patient with a brain tumor who has only a month to live meets a childlike, mentally challenged man, who becomes her traveling companion for a cross-country car trip that brings unexpected meaning to both their lives.

Homer and Eddie has an approval rating of 0% on review aggregator website Rotten Tomatoes, based on 7 reviews, and an average rating of 2.67/10.

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