It also features the voice work of Sinbad, Carla Gugino, Tisha Campbell-Martin, Stephen Tobolowsky, Jon Polito, Adam Goldberg, Al Michaels, Tommy Lasorda and Bob Uecker.

In addition, Robert Hays, Kim Greist, Veronica Lauren, Kevin Chevalia and Benj Thall reprised their roles for the sequel.

Shadow and Sassy follow his lead, and together after eluding airport authorities, the animals find themselves in the city of San Francisco.

As their journey begins, Chance unintentionally runs into a Boxer and his Bullmastiff friend; named Ashcan and Pete, respectively.

Acknowledging their differences regarding humans, Shadow and Sassy express their thanks to the group and continue to make their way towards the Golden Gate Bridge.

When the pair come upon a housefire and upon hearing the discussion of frantic parents and the San Francisco Fire Department Battalion Chief, they realize that a young boy and his kitten are still inside the house.

Shadow exits moments later with the boy by his side, as the porch collapses following a sudden backdraft of flames.

Riley begins to explain to the romantic couple that they are too different for each other, but together they disagree with his assessment and sleep outside the safe haven.

As the drivers try to avoid the attacking animals, a member of the gang named Bando enters the van, puts it in reverse, and backs it into the river.

The film holds a 56% aggregated critic approval rating on Rotten Tomatoes based on 18 reviews, indicating a below-average viewing score.

Debuting at #2 at the box office, Homeward Bound II: Lost in San Francisco remained in theatres for approximately five weekends.