It is mainly sold in Southeast Asia and also in other regions, positioned as an entry-level hatchback model slotted below the Fit/Jazz and the City.

[2] In August 2013 in Indonesia, several entry-level Brio variants received an additional Indonesia-inspired name to comply with the country's LCGC (Low Cost Green Car) program.

The car was specifically designed for emerging markets such as Thailand and India, two countries where the Brio was initially manufactured.

After the car was facelifted in May 2016, which included updated front fascia, taillights, and dashboard design, the manual transmission option was discontinued, leaving only the V grade with CVT.

The Brio's planned launch in India was delayed in early 2011 due to the 2011 Tōhoku earthquake and tsunami in Japan.

[12] The Indian market Brio was produced by the company's subsidiary, Honda Cars India Ltd (HCIL), at its production facilities in Greater Noida.

The Brio stopped production in India in November 2018 and removed from the lineup in February 2019 due to slow sales, leaving the Amaze as Honda's entry-level offering for the Indian market.

It used the 1.3-litre L13Z1 engine instead of the 1.2-litre L12B3 unit seen previously in the Thai and Indian market, which was initially mated to either a 5-speed manual or a 5-speed torque converter automatic transmission.

[17] Only the lower grades (A, S, and E, all with manual transmission) were initially qualified as an LCGC due to price limits imposed by the government.

The automatic 1.2-litre model (for S and E grades) was allegedly failed to qualify the LCGC regulations which require a fuel consumption of 20 km/L (56 mpg‑imp; 47 mpg‑US) under certain specific conditions, which made it liable for an extra luxury goods tax.

[18] The Indonesian market Brio received its facelift on 7 April 2016 at the 24th Indonesia International Motor Show.

[22] In May 2014, Honda issued a recall of about 32,000 Brio and Amaze cars in India due to a possible mis-assembly of the proportioning valve.

It was previewed by the Small RS Concept that was displayed at the 26th Indonesia International Motor Show in April 2018.

[27][28] Due to the falling demand in Thailand and India, the second-generation Brio is exclusively manufactured in Indonesia.

[29] For the Indonesian market, the second-generation Brio is available in the same grade levels as the facelifted first-generation model, with either manual transmission or CVT.

[39] Unlike the Indonesian market, the Philippine-market Brio RS doesn't get the push-to-start smart entry system and the optitron instrument gauge cluster as it retained the rotary-type ignition and the standard instrument cluster panel from the pre-facelift model.