Hongō-sanchōme Station (本郷三丁目駅, Hongō-sanchōme-eki) is a railway station in Bunkyō, Tokyo, Japan, jointly operated by the Tokyo subway operators Tokyo Metro and Toei Subway.

Part of the station originally lay within the Hongō-sanchōme district of Bunkyō Ward when the station was first opened, but following rezoning in 1965, the address of the station became Hongō-nichōme.

There is no underground connection between the platforms, so transfers require surfacing and re-entering.

The Tokyo Metro section of the station is composed of two side platforms serving two tracks.

The Toei section of the station is composed of a single island platform serving two tracks.