[3] In 2005, Ramírez finished with a record of 11–9 and an ERA of 4.63 in 33 games (32 starts), pitching over 200 innings for the first time in his career.

[1] On December 6, 2006, the Braves traded Ramírez to the Seattle Mariners for right-handed relief pitcher, Rafael Soriano.

[10] After his release from Kansas City, on June 15, 2009, Ramírez signed a minor league deal with the Washington Nationals.

On February 1, 2010, Ramírez signed a minor league contract with the San Francisco Giants.

On June 15, 2012, Ramírez signed with the Lancaster Barnstormers of the Atlantic League of Professional Baseball.

On July 5, 2013, Ramirez signed with the Tigres de Quintana Roo of the Mexican League.

[20] On March 5, 2016, Ramírez began a professional comeback signed with the Toros de Tijuana of the Mexican Baseball League.

For the 2019 season, Ramírez made 32 appearances for the Toros, pitching to a 4-0 record and 2.60 ERA with 9 strikeouts in 34.2 innings of work.

[22] He made 12 appearances (10 starts) for Tijuana in 2021, working to a 3-3 record and 4.50 ERA with 17 strikeouts in 50.0 innings pitched.

[25] On February 11, 2025, Ramírez was named pitching coach for the Rome Emperors, Atlanta's High-A affiliate.