Horntown is a town in Hughes County, Oklahoma, United States.

Horntown is the center of a dispersed rural community in Jacobs Township of Hughes County that formed in the 1920s.

The earliest inhabitants, according to the Encyclopedia of Oklahoma History and Culture, were T. C. Horn and Charley Hawthorn, who operated retail stores, garages, gasoline stations and a restaurant at the crossroads of two section-line roads that are now U.S.

Also in that year, the population of the immediate area served by Horntown's businesses included approximately 200 residents.

At that time, a convenience store–a restaurant, a gasoline station, and a tire store operated.

The Horntown fire department, law enforcement, and emergency services maintained a small complex of buildings, and the Banner Baptist Church served residents.

The two highways join in Horntown and lead south 8 miles (13 km) to Calvin.