Horo Guduru Welega (Oromo: Walllaga Horroo Guduruu) is a zone in Oromia Region of Ethiopia.
The seat of the zonal administration cabinet is in Shambu town.
In this zone, various community associations are working on supporting elderly, children, and youths suffering financially and lacking family support.
Based on the 2007 Census conducted by the Central Statistical Agency of Ethiopia (CSA), this zone has a total population of 570,040, of whom 285,515 are men and 284,525 are women.
The two largest ethnic groups reported in Horo Gudru Welega were the Oromo (93.12%) and the Amhara (6.34%); all other ethnic groups made up 0.54% of the population.