Horsehead Crossing is a ford on the Pecos River in Crane County, south of Odessa, Texas.

The ford was mapped in 1849 by Randolph B. Marcy, commander of an army escort for parties on their way to California on the San Antonio-El Paso Road.

In 1858, the crossing became an important stop on the Butterfield Overland Mail route from St. Louis to San Francisco.

[2] In 1866, Charles Goodnight and Oliver Loving blazed their famous cattle trail, which came to this point and turned upriver.

Decline of cattle drives and completion of two railroads across West Texas in the early 1880s led to the abandonment of the crossing.