Mirza Hossein-Qoli Khan Mafi (Persian: میرزا حسینقلی خان مافی; 1832 – 6 August 1908) titled Nezam al-Saltaneh (نظام السلطنه) was an Iranian politician serving as the prime minister of Iran from 21 December 1907 to 21 May 1908.

[3] Before becoming prime minister, Hossein-Qoli served as the governor of Bushehr (1857), Yazd (1874), Dashtestan (1875), Zanjan (1885), Khuzestan and Bakhtiari areas along with Chaharmahal (1887 and again in 1894), Azerbaijan (1899) and Fars.

He followed traditional social norms and, like his brother Mohammad-Hasan Khan, he was against the growing trend of many of their peers copying everything that was European.

Hossein-Qoli was a patron of the poets Iraj Mirza and Forsat-od-Dowleh Shirazi and was well-versed in classical Persian literature and Iranian history.

Hossein-Qoli described his tour to the ruins of the Sasanian city of al-Mada'in in Ottoman Iraq with a sarcastic sense of humor and a pragmatic approach to life in general.