The film returns most of the cast of the first film such as Kid 'n Play, Full Force, Tisha Campbell, and Martin Lawrence along with new cast members such as Iman, Queen Latifah, and Georg Stanford Brown and more guest appearances by other famous entertainers, such as Tony!

After high school graduation and his father's death, Kid, with scholarship money provided by the congregation of his church, goes off to college with his girlfriend, Sidney.

Play, now driving a Ford Mustang instead of his beat up old wagon, meets Sheila Landreaux and her associate Rick.

Unable to pay his tuition and enrollment fees, Kid tries to reason with the dean but is only given a week to gather the money he needs.

To top it off, Kid is hunted by his high school bullies, Stab, Zilla, and Pee Wee, who take jobs as campus security.

In order to raise the money he needs and win back Sidney, Kid, Play, Bilal and Jamal secretly hold a pajama themed party for the students in the faculty dining hall.

The party is a success as hundreds of students turn up wearing elaborate costumes and dance the night away, including to a performance by Kid and Play.

Eventually, Play sees the con artists trying to coerce Zora, Sidney’s socially conscious roommate.

He also says he is gonna visit the university periodically, seeing as Kid is his "investment" now moving back inside his dorm and Play driving off to the sunset.