Struggling sculptor Marcel de Lange is depressed about events in his life, and decides to commit suicide.

[4] Initially Kent Taylor was selected to play the part of Police Lt. Larry Brooks, but on the fourth day of production, before he was shot in any scenes, he was replaced by Bill Goodwin.

[4] The assistant director's daily reports suggest that this story was a lie, stating that Goodwin was the only person to play Brooks on set.

[5] Kosleck was particularly proud of his performance in the film, stating he received fan mail for it and he "loved that part".

[5] House of Horrors was shown in New York on February 22, 1946[2] and received wider release by Universal Pictures on March 29.

[8] From contemporary reviews, many critics commented on Rondo Hatton, with George H. Spires stating that his "Neanderthal features suffice without the aid of make up [...] and his ape-like appearance on the screen brings a gasp to the audience", while Edmond J. Bartnett of The New York Times said Hatton was "properly scary".

[9] As for the picture overall, a reviewer in Harrison's Reports wrote that "little about the proceedings to horrify one unless the fact that murders are committed by a half-witted giant can be considered horrendous rather than unpleasant".

Martin Kosleck is good as de Lange, his moments of insane hatred contrasting well with his more gentle moods.