The House of Ossoliński (plural: Ossolińscy) was a Polish aristocratic family from the Lesser Poland region.
The progenitor of the family was Jan of Ossolin [pl],[3] son of Great Marshal of the Crown and castellan of Kraków Nawoj of Tęczyn.
Jan was the main heir of the property that Nawoj left after his death.
Grand Chancellor of the Crown Jerzy Ossoliński was granted a hereditary princely title by Pope Urban VIII in 1633.
Another title was granted to Jerzy's cousin Franciszek Maksymilian Ossoliński by Louis XV, King of France, in 1736.