How to Murder Your Wife is a 1965 American black comedy film from United Artists, produced by George Axelrod, directed by Richard Quine, that stars Jack Lemmon and Virna Lisi.

Quine also directed Lemmon in My Sister Eileen, It Happened to Jane, Operation Mad Ball, The Notorious Landlady and Bell, Book and Candle.

While attending a bachelor party for his friend Tobey Rawlins, Stanley becomes intoxicated and somehow ends up marrying the beautiful Italian woman who appears out of a cake, with an equally drunk judge performing the impromptu wedding.

Stanley now finds his bathroom filled with beauty products and lingerie, and he is kept awake at night by his wife constantly watching television, which she says helps with her English.

As usual, he enacts the events live before drawing the strip, drugging his wife during a cocktail party, but using a department-store mannequin to play out her burial in the concrete from the mixer.

Facing a possible conviction, Stanley takes up his own defense and pleads justifiable homicide, appealing to the all-male jury's frustrations regarding their own wives and marriages.

Bosley Crowther of The New York Times wrote: "Never have I seen a movie, serious, comic or otherwise, that so frankly, deliberately and grossly belittled and ridiculed wives” and “this stuff is funny just so long as one can go with the sour joke—and that depends upon one's tolerance of trivia and also, perhaps, upon whether one is a fellow or a girl".