The studios are located in a densely populated neighborhood near Brandywine Park and the Delaware Avenue Historic District.

The building used by Pyle as his own studio was built in 1883, mainly in brick with a Tudor Revival half timbered gable.

The original studio was set back eighty feet from the street and has a steeply pitched roof.

One gable forms the main facade of the studio framing the entry porch and a triple casement window.

A total of 75 students attended between 1900 and 1911, including N.C. Wyeth, Frank Schoonover, Harvey Dunn, Stanley Arthurs, and George Harding.