The show is an episode-by-episode discussion of The West Wing, featuring guests from the cast and crew, as well as real-life political figures like Canadian Prime Minister Justin Trudeau, then-mayor Pete Buttigieg and White House Chief of Staff Ronald Klain.

Hirway is the host, producer, and editor of the Partners podcast, which features two people in noteworthy partnerships telling the story of how they met and how their dynamics work.

In the show's trailer, he says, “Every successful partnership, no matter what kind, is sort of a love story.” Vanity Fair called Partners one of the podcasts that defined 2020.

Along with chef and author Samin Nosrat, Hirway co-hosted the Home Cooking podcast, which they launched at the start of the COVID-19 pandemic.

It won the 2021 iHeartRadio award for Best Food Show, and was named one of the best podcasts of 2020 by Time,[2] Rolling Stone,[3] Vulture,[4] The Economist,[5] and The Atlantic.

The series features the artists Alicia Keys, Lin-Manuel Miranda, R.E.M., Ty Dolla Sign, Dua Lipa, Nine Inch Nails, Natalia Lafourcade, and The Killers.