Born in Shanghai, Hsu moved to Hong Kong to continue his professional career and never returned to the mainland China to play nor coach.
Due to the Second Sino-Japanese War, Hsu, along his international teammate, Liu Shih-Tsan, left for Hong Kong to continue his career.
[17][18] It was reported that along with Liu Shih-Tsan (Chinese: 劉始讚), they represented China in international tournaments in Shanghai.
[3] Due to the sponsorship of Singtao Sports Club owner Aw Hoe (Chinese: 胡好), Hsu was in the provisional squad of China national football team for 1948 Olympics.
[20] According to Lee Wai Tong, on top of as a footballer of Singtao Sports Club, Hsu was also employed as a journalist of sister company Sing Tao Daily.
[23] In 1961–62 season Hsu was hired as the manager (主任) of the football department (足球部) of Singtao Sports Club.
[26] In 1965–66 season, Hsu remained as the manager but assisted by a non-Chinese expatriate, known as 阿基 in the Chinese language media, as volunteering coach.
[27] Hsu was the manager and coach of Singtao in 1966–67 season, before leading Republic of China (Taiwan) in July 1967.
[29] He was the manager[nb 2] of Singtao in the next few seasons: (1968–69,[30][31] 1969–70,[32] 1970–71,[33] 1971–72[34] and 1972–73[35]) Since 1970 he also handed over some of the coaching job to his assistant Tam Hon Sun (譚漢新).
Hong Kong businessman Gordon Wu was also nominated as [honorary] manager (Chinese: 領隊) of the national team.
[49] Hsu was also nominated as manager[nb 5] and guest coach (Chinese: 教練) for the Hong Kong Football Association in November 1968 on a three-month contract, for friendlies against 1860 Munich in December[52] and 1969 Lunar New Year Cup against Odense.
[57] In June 1969 he was the coach of Hong Kong League XI[45][nb 8] for the exhibition matches against a team from UK and Borussia Mönchengladbach.
[63] Hsu also refused to lead Hong Kong in 1970 Pestabola Merdeka, due to the clash with Singtao pre-season tour,[62] making Jakarta Anniversary Tournament the only international match he led.
[77] Louis Hsu was involved in the invention of halo-pelvic traction, a medical operation led by John O'Brien.