The Hudson and Pepperdine Show is a comedy sketch show vehicle on BBC Radio 4 (repeated on BBC Radio 4 Extra) for the duo Melanie Hudson and Vicki Pepperdine.
They also did a single Afternoon Play in 2008 titled Hudson and Pepperdine Save the Planet.
Other regular cast members include Martin Hyder, Jim North, and Dave Lamb.
However, the show differs from a sitcom as the interactions of Hudson and Pepperdine simply serve to link together more traditional sketch based material with strands featuring a men's support group; rough neighbourhood girls; Edie Trinder, a pastiche of wartime radio comedy; and their upstairs neighbours, the 'Dirty Sloanes'.
The planned first show for the fourth and most recent series, scheduled to be broadcast on 7 July 2005, was pulled due to that day's terrorist attacks in London as it depicted Mel and Vicki's interaction with the government's emergency warning leaflet.