Eyton-Jones was brought up as a devoutly conservative Christian and was encouraged to develop an interest in theological, political and social matters.

[6] From 1886 to 1889 he was curate of St. Clement's, Birmingham, which is where he met Jane Elizabeth Savage, who would later become his wife, both of whom had a shared interest in volunteering and overseas missionary work.

[11] In March 1895 at the Consular District of Fuzhou where Eyton-Jones had opened a book shop having been provided a passport by the Prefect of Fujian, an attempt was made on his life by a follower of the zhaijiao "fasting school" who had been protesting against the Christian missionaries for some time,[12] the culprit drew a knife and ran at him before being rendered defenceless by eyewitnesses and was identified as a servant of the local magistrate and so received no punishment.

Ill health made him return to the United Kingdom in 1900, spending one year living with the family of his older brother John Eyton-Jones at Abbotsfield, Wrexham, before moving to London.

Throughout the war he worked closely with the YMCA, allowing the church hall to be used as a rest and social centre for military people stationed locally.

[15] A severe attack of shingles inspired him to write a letter of resignation to the bishop in the winter of 1942, however he died in the spring of 1943.