Hugh Ware Cross (August 24, 1896 – October 15, 1972) was an American politician, lawyer, farmer, and businessman who served as chairman of the Interstate Commerce Commission, lieutenant governor of Illinois, and speaker of the Illinois House of Representatives.

He practiced law in Jerseyville, Illinois, owned a farm, and was president of the Jersey County Abstract and Title Company.

In 1949, Cross was nominated by President Harry S. Truman to serve on the Interstate Commerce Commission (ICC).

Possible impropriety was alleged in Cross' provision of testimony as a character witness for shipping magnate John Keeshin.

While the matter he had testified in support of Keeshin on was intrastate (therefore not subject to ICC oversight), some senators nevertheless found it potentially untoward enough to investigate.