With Compound V: Hugh "Wee Hughie" Campbell is a fictional character and the protagonist of the comic book series The Boys and its spin-offs Herogasm and Highland Laddie, created by Garth Ennis and Darick Robertson and visually designed after Simon Pegg.
Hughie appears in the Amazon Prime Video television adaptation of the series as one of the main protagonists, where he serves as the moral compass and voice of reason of the Boys.
Hughie is portrayed by Jack Quaid in the television adaptation and resulting franchise, developed by Eric Kripke, with Simon Pegg portraying his father in the first, third and fourth seasons; while Pegg was originally attached to star in the series as Hughie, before development hell rendered him too old for the role, he would eventually voice the character in the animated anthology series The Boys Presents: Diabolical.
With his childhood friends, he played at being a boy detective; they had actually discovered a cigarette smuggling operation handled by a local pub owner.
Hughie first experiences the world of superhumans firsthand when his girlfriend Robin Mawhinney is accidentally killed by A-Train during a fight in which the latter is subduing another "Supe" while traveling faster than the speed of sound.
Due to this experience, Butcher recruits him to take Mallory's vacated spot on the Boys, and would later inject him with Compound V, without Hughie's permission.
As the series progressed, and the bloodshed gradually increased, Hughie would also grow angry with Butcher's dismissal of the constant violence ("big boys' rules") used in their operations.
Butcher was confused and irritated by the latter incidents, as he had advised him several times that the superhuman population largely does not care about normal people and are not worth his concern.
During the events of the attempted coup of the US Government by Homelander, Butcher captures A-Train with the hopes of getting Hughie to finally understand what it means to be one of The Boys.
It becomes clear that Butcher has been trying to get the team out of the way so he can carry out a mass murder of superhumans, even though the act will also likely kill those who only have trace amounts of V in their system – which, based on the accidental exposures of Compound V, would mean the deaths of billions of people.
With the help of Billy Butcher, he reluctantly decides to take vengeance on the Supes and joins his team, nicknamed "The Boys", which includes Frenchie, Mother's Milk "MM", and later Kimiko / The Female.
Hughie moves out of his father's apartment and continues on with the Boys' escapades, acting as their computer specialist, though he often experiences friction with Butcher and is constantly shell-shocked by the amount of carnage their missions cause.
The Boys discover Compound V and its role in the creation of Supes, finding a way to blackmail A-Train, who is addicted to the substance and was under its influence when he ran through Robin.
Annie is shocked when she discovers Hughie's association with the Boys and the truth about Compound V, but she helps him free MM, Frenchie, and Kimiko when they are abducted.
Concurrently, Annie, disillusioned by Vought, decides to secretly help the Boys and meets with Hughie at remote locations to exchange information, occasionally joining them in-person for certain missions.
In season three, Hughie finds out that Neuman is the head-popper when he witnesses her kill a childhood friend of hers from her days at Red River, a group home for orphaned Supes.
Investigating Neuman's past, Hughie discovers that she is the secret adoptive daughter of Vought CEO Stan Edgar (Giancarlo Esposito) and her anti-Vought policies are controlled opposition.
Realizing that his work for Neuman of the past year has been for nothing, he reaches out to Butcher to reform the Boys and take down Vought "his way", a decision leading to his own steady disillusionment.
Hughie then joins Butcher in recruiting Soldier Boy (Jensen Ackles) to their cause after accidentally freeing him from Russian captivity.
Hughie secures Compound V from A-Train to help his dying father, however he and Kimiko face an ambush from the Shining Light but they survive and get away.
In The Boys Presents: Diabolical episode "I'm Your Pusher", set in the same continuity as the Boys comic book series, Wee Hughie (voiced by Simon Pegg) and Butcher confront OD, a drug dealer who deals directly to Vought Supes, and blackmails him into tainting the Great Wide Wonder's drugs, causing him to crash into Ironcast during Great Wide Wonder's induction into the Vought Hall of Fame, killing them both.
[6][7] Hughie in the comics is a typical, average and regular male, possessing no superpowers or extraordinary abilities, until he is injected with a shot of Compound V.[8] The dosage applied to Wee Hughie is worth $19 billion, and gives him superhuman levels of strength and durability, the likes of which means he can casually injure and kill regular humans as well as some superhumans.
I doubt any twenty-something lad unused to trauma and violence could simply absorb it straightaway, and if he did become hardened or inured it would be as a different, less sensitive person.