Hugo Eduardo de León Rodríguez (born 27 February 1958) is a Uruguayan football coach and former player, who played as a defender.

The 189 cm defender was capped 48 times for Uruguay between July 1979 and June 1990, including four games at the 1990 World Cup.

De León helped the Uruguay national team win the 1980 Mundialito, a tournament celebrating the 50th anniversary of the first World Cup.

As a coach, De León was in charge of several clubs in Uruguay, Brazil and México, including Nacional, Gremio and Monterrey.

De León was a candidate for Vice President of Uruguay, alongside Pedro Bordaberry, in the 2009 Uruguayan general election.